Currently Principal Scientist, BMSF and Adjunct Senior Lecturer, UNSW School of Optometry and Vision Science.
Martin P Bucknall graduated from the University of Manchester BSc Physics (1987), and subsequently worked as an Instrumentation Engineer with Waters Corporation in England.
In 1994 he joined the Inherited Diseases of Metabolism Research Group at the King Faisal Specialist Hospital and Research Centre, in Riyadh, Saudi Arabia, where he played a key role in setting up the first neonatal screening program for Inherited Errors of Metabolism (IEM’s) in the Middle East. The analytical approach involved rapidly quantifying acylcarnitines and amino acids in dried blood spots (collected on filter paper and mailed into the laboratory) using stable isotope dilution flow injection electrospray tandem mass spectrometry. A data reduction algorithm (CAMPA) to recognize abnormal metabolite levels was successfully developed and evaluated by Martin and the team. This facilitated quantitative analysis of more than 30,000 samples for 27 biomarkers in just 2 years, using a single instrument.
Martin moved to UNSW in 1998 and worked as Research Services Manager at the Biomedical Mass Spectrometry Unit, eventually enrolling to study part-time in the School of Physiology and Pharmacology (Faculty of Medicine) for a PhD. His PhD research “Dityrosine as a biomarker of free radical induced oxidative damage in diseases of ageing”, involved measuring nanomolar levels of o, o’-dityrosine, with high levels of specificity, in human biological matrices and attempting to correlate levels (normalized to tyrosine or creatinine) with states of inflammation and subject age.
Since graduating in 2007, Martin has been employed as Principal Scientist (Small Molecule Analysis) at the Bioanalytical Mass Spectrometry Facility (BMSF) in the Mark Wainwright Analytical Centre (MWAC) at UNSW Sydney. His main role is the supervision of PhD and Postdoc work involving mass spectrometry for projects originating from research schools across the UNSW campus.
Martin also engages in commercial / legal / forensic analytical work and consulting.
Conference Papers
Gibson E;Bucknall M;Golebiowski B;Wolffsohn J;Stapleton F, 2017, 'Detection of sex steroids and their metabolites in human tears using LC-MS/MS', in
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Baltimore, MD, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Baltimore, MD, 07 - 11 May 2017,
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432170301088&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68aKoshy P;Choi SK;Adabifiroozjaei E;Gupta S;Sorrell CC;Bucknall M;Thomas D;Rawal A;Jang DM, 2017, 'Effect of Polymer Blending on the Properties of Coal Tars Produced by Pyrolysis', in Zeng Q;Bandyopadhyay S (eds.), Proceedings of iCMEMS Conference 2017, Science, Technology and Management Crest Australia, Sydney, pp. 45 - 50, presented at 1st International Conference on Mineral Engineering and Materials Science (iCMEMS2017), Sydney, 20 - 22 November 2017
Lim WW;Bucknall MP;Adler L;McKenzie DR;Suaning GJ, 2015, 'On the use of test gases of various radii to investigate molecular sieving in leak channels', in
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 813 - 816,
http://dx.doi.org/10.1109/EMBC.2015.7318486Bucknall, Martin P ;Chandra-Hioe, Maria Veronica ;Arcot, Jayashree, 2013, 'A practical approach toward monitoring folic acid levels in food. A first look at whether Australian breads and bread-making flour contain the fortified folate levels mandated in 2009.', in Khairallah, George (ed.), ANZSMS24 Conference Program, 24th Australian and New Zealand Society for Mass Spectrometry, Trinity College (University of Melbourne), Parkville, Victoria, Australia, presented at 24th Australian and New Zealand Society for Mass Spectrometry, Trinity College (University of Melbourne), Parkville, Victoria, Australia, 02 - 06 February 2013
Chandra-hioe M;Bucknall MP;Arcot J, 2012, 'Ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS): development, optimisation and validation of the method used for folate analysis in foods', in Technology for Food Quality, Technology for Food Quality, Brisbane Australia, pp. 12 - 18, presented at 12th Government Food Analysts Conference, Brisbane Australia, 22 - 24 February 2011
Conference Posters
Chandra-hioe M;Bucknall MP;Pickford R;Arcot J, 2010, 'The levels of Folic Acid and 5-Methyl Tetra Hydrofolate in Australian fortified bread', Copenhagen, presented at 1st International Vitamin Conference, Copenhagen, 19 - 21 May 2010
Chandra-hioe M;Bucknall MP;Pickford R;Arcot J, 2010, 'The Levels of Folic Acid and 5-Methyl Tetrahydrofolate in Australian Fortified Breads', Copenhagen, presented at 1st International Vitamin Conference, Copenhagen, 19 - 21 May 2010
Journal articles
Phan MA T;Bucknall MP;Arcot J, 2019, 'Effects on intestinal cellular bioaccessibility of carotenoids and cellular biological activity as a consequence of co-ingestion of anthocyanin- and carotenoid-rich vegetables',
Food Chemistry, vol. 286, pp. 678 - 685,
http://dx.doi.org/10.1016/j.foodchem.2019.02.046Gibson EJ;Bucknall MP;Golebiowski B;Stapleton F, 2019, 'Comparative limitations and benefits of liquid chromatography – mass spectrometry techniques for analysis of sex steroids in tears',
Experimental Eye Research, vol. 179, pp. 168 - 178,
http://dx.doi.org/10.1016/j.exer.2018.11.015Phan MA T;Bucknall MP;Arcot J, 2019, 'Interferences of anthocyanins with the uptake of lycopene in Caco-2 cells, and their interactive effects on anti-oxidation and anti-inflammation in vitro and ex vivo',
Food Chemistry, vol. 276, pp. 402 - 409,
http://dx.doi.org/10.1016/j.foodchem.2018.10.012Phan MA T;Bucknall M;Arcot J, 2018, 'Effect of different anthocyanidin glucosides on lutein uptake by Caco-2 cells, and their combined activities on anti-oxidation and anti-inflammation in vitro and ex vivo',
Molecules, vol. 23,
http://dx.doi.org/10.3390/molecules23082035Saha B;Bucknall M;Arcot J;Driscoll R, 2018, 'Derivation of two layer drying model with shrinkage and analysis of volatile depletion during drying of banana',
Journal of Food Engineering, vol. 226, pp. 42 - 52,
http://dx.doi.org/10.1016/j.jfoodeng.2018.01.010Saha B;Bucknall MP;Arcot J;Driscoll R, 2018, 'Profile changes in banana flavour volatiles during low temperature drying',
Food Research International, vol. 106, pp. 992 - 998,
http://dx.doi.org/10.1016/j.foodres.2018.01.047Kumar U;Gaikwad V;Mayyas M;Bucknall M;Sahajwalla V, 2018, 'Application of High-Resolution NMR and GC-MS to Study Hydrocarbon Oils Derived from Noncatalytic Thermal Transformation of e-Waste Plastics',
ACS Omega, vol. 3, pp. 9282 - 9289,
http://dx.doi.org/10.1021/acsomega.8b01284Phan MA T;Bucknall M;Arcot J, 2018, 'Interactive effects of β-carotene and anthocyanins on cellular uptake, antioxidant activity and anti-inflammatory activity in vitro and ex vivo',
Journal of Functional Foods, vol. 45, pp. 129 - 137,
http://dx.doi.org/10.1016/j.jff.2018.03.021Phan MA T;Paterson J;Bucknall M;Arcot J, 2018, 'Interactions between phytochemicals from fruits and vegetables: Effects on bioactivities and bioavailability',
Critical Reviews in Food Science and Nutrition, vol. 58, pp. 1310 - 1329,
http://dx.doi.org/10.1080/10408398.2016.1254595Das B;Ezzedinloo L;Bhadbhade M;Bucknall MP;Colbran SB, 2017, 'Strategic design of a ruthenium catalyst for both CO
2 reduction and H
2O oxidation: The electronic influence of the co-ligands',
Chemical Communications, vol. 53, pp. 10006 - 10009,
http://dx.doi.org/10.1039/c7cc06294jCarthey AJ R;Bucknall MP;Wierucka K;Banks PB, 2017, 'Novel predators emit novel cues: A mechanism for prey naivety towards alien predators',
Scientific Reports, vol. 7,
http://dx.doi.org/10.1038/s41598-017-16656-zChandra-Hioe MV;Bucknall MP;Arcot J, 2017, 'Evaluating folate extraction from infant milk formulae and adult nutritionals: Enzymatic digestion versus enzyme-free heat treatment',
Food Chemistry, vol. 234, pp. 365 - 371,
http://dx.doi.org/10.1016/j.foodchem.2017.04.179Mayyas M;Pahlevani F;Bucknall M;Maroufi S;You Y;Liu Z;Sahajwalla V, 2017, 'Thermocatalytic Conversion of Automotive Shredder Waste and Formation of Nanocarbons as a Process Byproduct',
ACS Sustainable Chemistry and Engineering, vol. 5, pp. 5440 - 5448,
http://dx.doi.org/10.1021/acssuschemeng.7b00774Kumar RK;Shadie AM;Bucknall MP;Rutlidge H;Garthwaite L;Herbert C;Halliburton B;Parsons KS;Wark PA B, 2015, 'Differential injurious effects of ambient and traffic-derived particulate matter on airway epithelial cells',
Respirology, vol. 20, pp. 73 - 79,
http://dx.doi.org/10.1111/resp.12381Jacobs W;Feng P;Austad J;Austin S;Bacler S;Barrett B;Bhandari S;Blake C;Boison J;Brown A;Bucknall M;Campos-Giménez E;Cellar N;Cenky M;Christiansen S;Clifford R;Collison M;Cruijsen H;De Borba BD;Deborde JL;De Guzman R;De Laat M;Deng XJ;DeVreeze M;Dubois-Lozier A;Ellefson WC;Embuscado M;Evers J;Fruth J;Gill BD;Golay PA;Haselberger P;Holskey M;Holroyd S;Hostetler G;Huang M;Indyk H;Jaudzems G;Jobgen E;Joseph G;Klarenbeek B;Kneeteman E;Kohler K;Konings EJ M;Lacorn M;Liang LX;Lock S;Marley E;Martin F;McMahon A;Phillips MM;Messerly J;Mohindra D;Montgomery N;Mountford M;Nipales N;Ofitserova M;Pacquette L;Pan SJ;Phillips S;Poitevin E;Poland A;Rankin R;Reimann L;Reuther J;Rimmer CA;Romano J;Royce S;Salvati L;Schmitz D;Shippar J;Sliva M;Song A;Steele K;Sullivan D;Szpylka J;Thompson JJ;Thompson L;Thompson M;Torma L;Rodriguez MT;Vermeulen M;Wargo W;Wood L;Woollard D;Wolf W;Yang J;Zhao L;Zhou Y;Zywicki R;Coates S, 2015, 'Determination of amino acids in infant formula and adult/pediatric nutritional formula',
Journal of AOAC International, vol. 98, pp. 1073 - 1076,
http://dx.doi.org/10.5740/jaoac.int.SMPR2014.013Jacobs W;Feng P;Austad J;Austin S;Bacler S;Barrett B;Bhandari S;Blake C;Boison J;Brown A;Bucknall M;Campos-Giménez E;Cellar N;Cenky M;Christiansen S;Clifford R;Collison M;Cruijsen H;De Borba BD;Deborde JL;De Guzman R;De Laat M;Deng XJ;DeVreeze M;Dubois-Lozier A;Ellefson WC;Embuscado M;Evers J;Fruth J;Gill BD;Golay PA;Haselberger P;Holskey M;Holroyd S;Hostetler G;Huang M;Indyk H;Jaudzems G;Jobgen E;Joseph G;Klarenbeek B;Kneeteman E;Kohler K;Konings EJ M;Lacorn M;Liang LX;Lock S;Marley E;Martin F;McMahon A;Phillips MM;Messerly J;Mohindra D;Montgomery N;Mountford M;Nipales N;Ofitserova M;Pacquette L;Pan SJ;Phillips S;Poitevin E;Poland A;Rankin R;Reimann L;Reuther J;Rimmer CA;Romano J;Royce S;Salvati L;Schmitz D;Shippar J;Sliva M;Song A;Steele K;Sullivan D;Szpylka J;Thompson JJ;Thompson L;Thompson M;Torma L;Rodriguez MT;Vermeulen M;Wargo W;Wood L;Woollard D;Wolf W;Yang J;Zhao L;Zhou Y;Zywicki R;Coates S, 2015, 'Determination of selected carotenoids in infant formula and adult/pediatric nutritional formula',
Journal of AOAC International, vol. 98, pp. 1077 - 1078,
http://dx.doi.org/10.5740/jaoac.int.SMPR2014.014Jacobs W;Feng P;Austad J;Austin S;Bacler S;Barrett B;Bhandari S;Blake C;Boison J;Brown A;Bucknall M;Campos-Giménez E;Cellar N;Cenky M;Christiansen S;Clifford R;Collison M;Cruijsen H;De Borba BD;Deborde JL;De Guzman R;De Laat M;Deng XJ;DeVreeze M;Dubois-Lozier A;Ellefson WC;Embuscado M;Evers J;Fruth J;Gill BD;Golay PA;Haselberger P;Holskey M;Holroyd S;Hostetler G;Huang M;Indyk H;Jaudzems G;Jobgen E;Joseph G;Klarenbeek B;Kneeteman E;Kohler K;Konings EJ M;Lacorn M;Liang LX;Lock S;Marley E;Martin F;McMahon A;Phillips MM;Messerly J;Mohindra D;Montgomery N;Mountford M;Nipales N;Ofitserova M;Pacquette L;Pan SJ;Phillips S;Poitevin E;Poland A;Rankin R;Reimann L;Reuther J;Rimmer CA;Romano J;Royce S;Salvati L;Schmitz D;Shippar J;Sliva M;Song A;Steele K;Sullivan D;Szpylka J;Thompson JJ;Thompson L;Thompson M;Torma L;Rodriguez MT;Vermeulen M;Wargo W;Wood L;Woollard D;Wolf W;Yang J;Zhao L;Zhou Y;Zywicki R;Coates S, 2015, 'Determination of chloride in infant formula and adult/pediatric nutritional formula',
Journal of AOAC International, vol. 98, pp. 1079 - 1080,
http://dx.doi.org/10.5740/jaoac.int.SMPR2014.015Blake C;Austad J;Austin S;Bacler S;Barrett B;Bhandari S;Boison J;Brown A;Bucknall M;Campos-Giménez E;Cellar N;Cenky M;Christiansen S;Clifford R;Collison M;Cruijsen H;De Borba B;Deborde JL;De Guzman R;De Laat M;Deng XJ;De Vreeze M;Dubois-Lozier A;Ellefson WC;Embuscado M;Evers J;Feng P;Fruth J;Gill BD;Golay PA;Haselberger P;Holskey M;Holroyd S;Hostetler G;Huang M;Indyk H;Jacobs W;Jaudzems G;Jobgen E;Joseph G;Klarenbeek B;Kneeteman E;Kohler K;Konings EJ M;Lacorn M;Liang LX;Lock S;Marley E;Martin F;McMahon A;Phillips MM;Messerly J;Mohindra D;Montgomery N;Mountford M;Nipales N;Ofitserova M;Pacquette L;Pan SJ;Phillips S;Poitevin E;Poland A;Rankin R;Reimann L;Reuther J;Rimmer CA;Romano J;Royce S;Salvati L;Schmitz D;Shippar J;Sliva M;Song A;Steele K;Sullivan D;Szpylka J;Thompson JJ;Thompson L;Thompson M;Torma L;Rodriguez MT;Vermeulen M;Wargo W;Wood L;Woollard D;Wolf W;Yang J;Zhao L;Zhou Y;Zywicki R;Coates S, 2015, 'Determination of fluoride in infant formula and adult/pediatric nutritional formula',
Journal of AOAC International, vol. 98, pp. 1081 - 1082,
http://dx.doi.org/10.5740/jaoac.int.SMPR2014.016Mcskimming A;Diachenko V;London R;Olrich K;Onie CJ;Read RW;Colbran SB;Bhadbhade MM;Bucknall MP, 2014, 'An easy one-pot synthesis of diverse 2,5-di(2-pyridyl)pyrroles: A versatile entry point to metal complexes of functionalised, meridial and tridentate 2,5-di(2-pyridyl)pyrrolato ligands',
Chemistry - A European Journal,
http://dx.doi.org/10.1002/chem.201402157Luu W;Zerenturk EJ;Kristiana I;Bucknal MP;Sharpe LJ;Brown AJ, 2014, 'Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesi[s]',
Journal of Lipid Research, vol. 55, pp. 410 - 420,
http://dx.doi.org/10.1194/jlr.M043257Chandra-Hioe MV;Bucknall MP;Arcot J, 2013, 'Folic Acid-fortified Flour: Optimised and Fast Sample Preparation Coupled with a Validated High-Speed Mass Spectrometry Analysis Suitable for a Fortification Monitoring Program',
Food Analytical Methods, vol. 6, pp. 1416 - 1423,
http://dx.doi.org/10.1007/s12161-012-9559-3Chandra-Hioe MV;Addepalli R;Osborne SA;Slapetova I;Whan R;Bucknall MP;Arcot J, 2013, 'Transport of folic acid across Caco-2 cells is more effective than 5-methyltetrahydrofolate following the in vitro digestion of fortified bread',
Food Research International, vol. 53, pp. 104 - 109,
http://dx.doi.org/10.1016/j.foodres.2013.03.044Chandra-Hioe MV;Bucknall MP;Arcot J, 2011, 'Folate analysis in foods by UPLC-MS/MS: Development and validation of a novel, high throughput quantitative assay; Folate levels determined in Australian fortified breads',
Analytical and Bioanalytical Chemistry, vol. 401, pp. 1035 - 1042,
http://dx.doi.org/10.1007/s00216-011-5156-3Stangoulis J;Tate M;Graham R;Bucknall M;Palmer L;Boughton B;Reid R, 2010, 'The mechanism of boron mobility in wheat and canola phloem',
Plant Physiology, vol. 153, pp. 876 - 881,
http://dx.doi.org/10.1104/pp.110.155655Chen V;Chan R;Li H;Bucknall MP, 2007, 'Spatial distribution of foulants on membranes during ultrafiltration of protein mixtures and the influence of spacers in the feed channel',
Journal of Membrane Science, vol. 287, pp. 79 - 87,
http://dx.doi.org/10.1016/j.memsci.2006.10.017Chan R;Chen V;Bucknall MP, 2004, 'Quantitative Analysis of Membrane Fouling by Protein Mixtures Using MALDI-MS',
Biotechnology and Bioengineering, vol. 85, pp. 190 - 201,
http://dx.doi.org/10.1002/bit.10866Swanson RL;Williamson JE;De Nys R;Kumar N;Bucknall MP;Steinberg PD, 2004, 'Induction of settlement of larvae of the sea urchin Holopneustes purpurascens by histamine from a host alga',
Biological Bulletin, vol. 206, pp. 161 - 172,
http://dx.doi.org/10.2307/1543640Chan R;Chen V;Bucknall MP, 2002, 'Ultrafiltration of protein mixtures: Measurement of apparent critical flux, rejection performance, and identification of protein deposition',
Desalination, vol. 146, pp. 83 - 90,
http://dx.doi.org/10.1016/S0011-9164(02)00493-9Bucknall M;Fung KY C;Duncan MW, 2002, 'Practical quantitative biomedical applications of MALDI-TOF mass spectrometry',
Journal of the American Society for Mass Spectrometry, vol. 13, pp. 1015 - 1027,
http://dx.doi.org/10.1016/S1044-0305(02)00426-9Rahbeeni Z;Vaz FM;Al-Hussein K;Bucknall MP;Ruiter J;Wanders RJ;Rashed MS, 2002, 'Identification of two novel mutations in OCTN2 from two Saudi patients with systemic carnitine deficiency',
Journal of Inherited Metabolic Disease, vol. 25, pp. 363 - 369,
http://dx.doi.org/10.1023/A:1020143632011Soufi S;Rashed MS;Al Essa M;Bucknall MP;Refi A;Badaghesh F;Habib HS;Ozand PT, 1998, 'Glutaric acidemia type 1: First Saudi patient diagnosed by tandem mass spectrometry-based neonatal screening',
Annals of Saudi Medicine, vol. 18, pp. 160 - 163,
http://dx.doi.org/10.5144/0256-4947.1998.160Rashed MS;Bucknall MP;Little D;Awad A;Jacob M;Alamoudi M;Alwattar M;Ozand PT, 1997, 'Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microplate batch process and a computer algorithm for automated flagging of abnormal profiles', Clinical Chemistry, vol. 43, pp. 1129 - 1141
Rashed MS;Ozand PT;Bucknall MP;Little D, 1995, 'Diagnosis of inborn errors of metabolism from blood spots by acylcarnitines and amino acids profiling using automated electrospray tandem mass spectrometry',
Pediatric Research, vol. 38, pp. 324 - 331,
http://dx.doi.org/10.1203/00006450-199509000-00009
