Dr Alex Macmillan
Senior Lecturer
Facility:
Publications
Book Chapters
Carnell M; Macmillan A; Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', in Methods in Membrane Lipids: Second Edition, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18
Macmillan A; Cranfield CG; Martinac B, 2014, 'Fluorescence methods for monitoring mechanosensitive channels', in Handbook of Imaging in Biological Mechanics, pp. 425 - 431, http://dx.doi.org/10.1201/b17566
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Conference Papers
Karolin J; Pánek D; MacMillan A; Rolinski O; Birch D, 2009, 'Fluorescence biosensing in nanopores', in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, pp. 4154 - 4157, http://dx.doi.org/10.1109/IEMBS.2009.5333940
Macmillan AM; McGuinness CD; Sagoo K; McLoskey D; Pickup JC; Birch DJS, 2008, 'Effect of pH on aqueous phenylalanine studied using a 265-nm pulsed light-emitting diode', in Annals of the New York Academy of Sciences, pp. 300 - 304, http://dx.doi.org/10.1196/annals.1430.056
Sutter JU; Macmillan AM; Birch DJS; Rolinski OJ, 2008, 'Toward single-metal-ion sensing by Förster resonance energy transfer', in Annals of the New York Academy of Sciences, pp. 62 - 67, http://dx.doi.org/10.1196/annals.1430.037
Journal articles
Eslami M; Zeglio E; Alosaimi G; Yan Y; Ruprai H; Macmillan A; Seidel J; Lauto A; Joukhdar H; Rnjak-Kovacina J; Mawad D, 2020, 'A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes', Macromolecular Bioscience, vol. 20, http://dx.doi.org/10.1002/mabi.202000103
Ridone P; Pandzic E; Vassalli M; Cox CD; Macmillan A; Gottlieb PA; Martinac B, 2020, 'Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters', Journal of General Physiology, vol. 152, http://dx.doi.org/10.1085/jgp.201912515
Sitiwin E; Madigan MC; Gratton E; Cherepanoff S; Conway RM; Whan R; Macmillan A, 2019, 'Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-019-54871-y
Cao C; Zhao J; Chen F; Lu M; Khine YY; Macmillan A; Garvey CJ; Stenzel MH, 2018, 'Drug-Induced Morphology Transition of Self-Assembled Glycopolymers: Insight into the Drug-Polymer Interaction', Chemistry of Materials, vol. 30, pp. 5227 - 5236, http://dx.doi.org/10.1021/acs.chemmater.8b01882
Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, vol. 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
Yasarapudi VB; Frazer L; Davis NJLK; Booker EP; Macmillan A; Gallaher JK; Roberts D; Perrier S; Schmidt TW, 2018, 'Optimization of energy transfer in a polymer composite with perylene chromophores', Journal of Materials Chemistry C, vol. 6, pp. 7333 - 7342, http://dx.doi.org/10.1039/c8tc02457j
Yasarapudi VB; Frazer L; Webb JEA; Gallaher JK; MacMillan A; Falber A; Thordarson P; Schmidt TW, 2018, 'Competing Energy Transfer Pathways in a Five-Chromophore Perylene Array', Journal of Physical Chemistry C, vol. 122, pp. 13937 - 13943, http://dx.doi.org/10.1021/acs.jpcc.8b01084
Chua SW; Cornejo A; Van Eersel J; Stevens CH; Vaca I; Cueto M; Kassiou M; Gladbach A; Macmillan A; Lewis L; Whan R; Ittner LM, 2017, 'The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons', ACS Chemical Neuroscience, vol. 8, pp. 743 - 751, http://dx.doi.org/10.1021/acschemneuro.6b00433
Ittner A; Chua SW; Bertz J; Volkerling A; Van Der Hoven J; Gladbach A; Przybyla M; Bi M; Van Hummel A; Stevens CH; Ippati S; Suh LS; Macmillan A; Sutherland G; Kril JJ; Silva APG; Mackay J; Poljak A; Delerue F; Ke YD; Ittner LM, 2016, 'Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice', Science, vol. 354, pp. 904 - 908, http://dx.doi.org/10.1126/science.aah6205
Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113
Constantine M; Liew CK; Lo V; MacMillan A; Cranfield CG; Sunde M; Whan R; Graham RM; Martinac B, 2016, 'Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep19352
Yaffe Y; Hugger I; Yassaf IN; Shepshelovitch J; Sklan EH; Elkabetz Y; Yeheskel A; Pasmanik-Chor M; Benzing C; Macmillan A; Gaus K; Eshed-Eisenbach Y; Peles E; Hirschberg K, 2015, 'The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex', Journal of Cell Science, vol. 128, pp. 2293 - 2302, http://dx.doi.org/10.1242/jcs.166249
Carnell M; Macmillan A; Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', Methods in Molecular Biology, vol. 1232, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18
Li Y; Duong HTT; Laurent S; Macmillan A; Whan RM; Elst LV; Muller RN; Hu J; Lowe A; Boyer C; Davis TP, 2015, 'Nanoparticles based on star polymers as theranostic vectors: Endosomal-triggered drug release combined with mri sensitivity', Advanced Healthcare Materials, vol. 4, pp. 148 - 156, http://dx.doi.org/10.1002/adhm.201400164
Sevimli S; Sagnella S; Macmillan A; Whan R; Kavallaris M; Bulmus V; Davis TP, 2015, 'The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers', Biomaterials Science, vol. 3, pp. 323 - 335, http://dx.doi.org/10.1039/c4bm00224e
Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, vol. 7, http://dx.doi.org/10.1186/s13221-014-0027-2
Dunn AE; Dunn DJ; Macmillan A; Whan R; Stait-Gardner T; Price WS; Lim M; Boyer C, 2014, 'Spatial and temporal control of drug release through pH and alternating magnetic field induced breakage of Schiff base bonds', Polymer Chemistry, vol. 5, pp. 3311 - 3315, http://dx.doi.org/10.1039/C4PY00150H
Sagnella SM; Hien D; MacMillan A; Boyer C; Whan R; McCarroll JA; Davis TP; Kavallaris M, 2014, 'Dextran-Based Doxorubicin Nanocarriers with Improved Tumor Penetration', BIOMACROMOLECULES, vol. 15, pp. 262 - 275, http://dx.doi.org/10.1021/bm401526d
Chang T; Lord MS; Bergmann B; MacMillan A; Stenzel MH, 2014, 'Size effects of self-assembled block copolymer spherical micelles and vesicles on cellular uptake in human colon carcinoma cells', Journal of Materials Chemistry B, vol. 2, pp. 2883 - 2891, http://dx.doi.org/10.1039/c3tb21751e
Salvemini IL; Gau DM; Reid J; Bagatolli LA; Macmillan A; Moens PDJ, 2014, 'Low PIP2 molar fractions induce nanometer size clustering in giant unilamellar vesicles', Chemistry and Physics of Lipids, vol. 177, pp. 51 - 63, http://dx.doi.org/10.1016/j.chemphyslip.2013.11.003
Boyer CA, 2013, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, vol. 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y
Basuki JS; Duong HTT; Macmillan A; Erlich RB; Esser L; Akerfeldt MC; Whan RM; Kavallaris M; Boyer C; Davis TP, 2013, 'Using Fluorescence Lifetime Imaging Microscopy to Monitor Theranostic Nanoparticle Uptake and Intracellular Doxorubicin Release', ACS NANO, vol. 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g
Basuki JS; Duong HTT; Boyer C; MacMillan A; Whan R; Davis TP, 2013, 'Polymer-grafted, nonfouling, magnetic nanoparticles designed to selectively store and release molecules via ionic interactions', Macromolecules, vol. 46, pp. 7043 - 7054, http://dx.doi.org/10.1021/ma401171d
Boris M; Battle A; Nomura T; Constantine M; Cranfield C, 2012, 'Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, pp. 8770 - 8775, http://dx.doi.org/10.1073/pnas.1200051109
Karolin J; Pánek D; MacMillan A; Rolinski O; Birch D, 2009, 'Fluorescence biosensing in nanopores.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 4154 - 4157
MacMillan AM; Panek D; McGuinness CD; Pickup JC; Graham D; Smith WE; Birch DJS; Karolin J, 2009, 'Improved biocompatibility of protein encapsulation in sol-gel materials', Journal of Sol-Gel Science and Technology, vol. 49, pp. 380 - 384, http://dx.doi.org/10.1007/s10971-008-1883-0
McGuinness CD; MacMillan AM; Karolin J; Smith WE; Graham D; Pickup JC; Birch DJS, 2007, 'Single molecule level detection of allophycocyanin by surface enhanced resonance Raman scattering', Analyst, vol. 132, pp. 633 - 634, http://dx.doi.org/10.1039/b706409h
McGuinness CD; Macmillan AM; Sagoo K; McLoskey D; Birch DJS, 2006, 'Excitation of fluorescence decay using a 265 nm pulsed light-emitting diode: Evidence for aqueous phenylalanine rotamers', Applied Physics Letters, vol. 89, http://dx.doi.org/10.1063/1.2245441
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Location
LG12, Lower Ground, Lowy Cancer Research Centre C25
